後代的性別比例是與母親月經初潮的年齡有關

Hum Reprod. 2011 Jun;26(6):1551-4. Epub 2011 Apr 5. (搶鮮版)

 

 

來自日本的研究

 

 

 

後代的性別比例是與母親月經初潮的年齡有關 

摘要


 

提前月經初潮(初經)的年齡是乳癌和卵巢癌的危險因素,也與增加自然流產率。

 

目的

 

是探討是否有早期月經初潮年齡之間和後代的性別比例的關聯。

 

方法

 

我們記錄了10 847停經前婦女(平均出席年齡:37.5 ± 7.2歲,範圍 22-54歲)共生出21208活產出生嬰兒的性別,參加了我們的產科和婦科診所的評估。我們計算的新生兒性別比例相對於母親的月經初潮年齡(從 918歲),向每名婦女生育的嬰兒數(即生育指數)。

 

結果

 

觀察母親誰進入初潮年齡在9;的比值比(OR)(95%置信區間)相比,有低後代的性別比例(男/女)的0.800(女多男少),那些與對照組 14歲初潮為 0.720.29-1.79)。在性別比例仍然很低,直到該組的母親誰進入初潮在12 [1.009OR0.900.85-0.95]。性別比最高(逐漸男多女少),觀察母親與月經初潮年齡 14歲(1.118OR1.00控制),它逐漸下降,直至月經初潮年齡 17 [1.000; OR0.890.15-5.26](男女平衡)。婦女月經初潮年齡在9歲至11歲,生育率指數(胎數)也很低,。

 

結論

女性進入月經初潮超出正常範圍,特別是那些月經初潮早,可能有增加的機會生女生。 

PS: 懷孕時baby的性別一直是所有懷孕夫妻最關切的,初經早多生女,這來自同是黃種人的日本的統計研究,很有趣。參考之!

 


Hum Reprod. 2011 Jun;26(6):1551-4. Epub 2011 Apr 5.

The sex ratio of offspring is associated with the mothers’ age at menarche.

Fukuda MFukuda KShimizu TNobunaga MGrete Byskov AYding Andersen C.

Source

M&K Health Institute, 30-9 Kariya, Ako, Hyogo 678-0239, Japan .

Abstract

BACKGROUND Early menarcheal age is a risk factor for breast and ovarian cancers and is also associated with an increased spontaneous abortion rate. The aim of this study was to investigate whether there is a link between early menarcheal age and the offspring sex ratio. METHODS We recorded the sex of 21208 live born infants, all singletons, born to 10 847 premenopausal women (mean attending age: 37.5 ± 7.2 years, range 22-54) who attended our clinics for obstetrical and gynaecological assessment. We calculated the sex ratio of newborn infants in relation to the mothers’ age of menarche (from 9 to 18 years) and to the number of infants per woman (i.e. fertility index). RESULTS A low offspring sex ratio (males/females) of 0.800 was observed in mothers who entered menarche at the age of 9 years; the odds ratio (OR) (95% confidence intervals) compared with those of control group with menarche at age 14 was 0.72 (0.29-1.79). The sex ratio remained low, until the group of mothers who entered menarche at 12 years of age [1.009; OR: 0.90 (0.85-0.95)]. The highest sex ratio was observed in mothers with a menarcheal age of 14 years (1.118; OR: 1.00 control) and it gradually decreased until the menarcheal age of 17 years [1.000; OR: 0.89 (0.15-5.26)]. The fertility index was also low in women with menarche at the age of 9 to 11 years. CONCLUSIONS Women entering menarche outside the normal range, especially those with earlier menarche, may have an increased chance of producing female offspring.

 

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陳啟煌

學位: 國防醫學院醫學系畢業(1985/08 - 1992/07) 台北醫學大學臨床醫學研究所博士畢業 (2012) 現職: 臺北醫學大學附設醫院婦產部不孕症科主任(2016.08~迄今) 臺北醫學大學醫學系婦產學科部定專任副教授 (2015年2月起~迄今) 經歷: 三軍總醫院婦產部住院醫師(1994/08 - 1999/07) 三軍總醫院婦產部主治醫師(1999/08 - 2011/02) 台灣駐查德共和國醫療團團長 (1999/08-2000/07) 美國Northwestern University試管嬰兒及人工生殖臨床研究員(2001/05~2002/04) 美國Johns Hopkins University生殖內分泌不孕症臨床研究員 (2001/04-2002/05) 國防醫學院婦產學科部定專任助理教授 臺北醫學大學醫學系婦產學科部定專任助理教授 臺北醫學大學附設醫院婦產部不孕症科主任(2016.08~迄今) 臺北醫學大學醫學系婦產學科部定專任副教授 (2015年2月起~迄今) 國際生殖保存醫學會Newsletter, co-editor 任期一年 中國婦幼保健協會聘任陳啟煌為中國婦幼保健協會生育力保存專家委員會顧問,聘期五年 (2017/11迄今) 海峽兩岸醫藥衛生交流協會生殖醫學分會第壹屆委員會副主任委員,任期三年 (2018/06/08~迄今) 台灣生殖醫學會副秘書長 (2018/09~2020/08)